Unmodified Titanium Dioxide Nanoparticles as a Potential Contrast Agent in Photon Emission Computed Tomography

نویسندگان

چکیده

Highly crystalline titanium dioxide nanoparticles (TiO2-NPs) are synthesized via a simple hydrothermal technique. After structural and compositional analysis, the as-synthesized unmodified TiO2-NPs tested for improvement in two modes of kilovoltage radiation therapy single-photon emission computed tomography (SPECT)/computed (CT). Our results show that provide an observable enhancement CT scan image contrast ranging from 0 ± 3 HU (without NPs) to 283.7 (0.23 g/mL). has excellent biocompatibility, selective uptake at target sites, reduced toxicity. The as agent can significantly improve existing methods diagnosing treating cancer.

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ژورنال

عنوان ژورنال: Crystals

سال: 2021

ISSN: ['2073-4352']

DOI: https://doi.org/10.3390/cryst11020171